Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BCL6 | P41182 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829652 | 0.85 | BCL6 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19BCL6 | |
| SCHEMBL5032257 | 0.80 | BCL6 (0.39) | BCL6MAPTGAANPC1RAB9A | |
| SCHEMBL6209798 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19BCL6 | |
| SCHEMBL4840694 | 0.74 | BCL6 (0.52) | BCL6MAPTGAANPC1RAB9A | |
| SCHEMBL4829068 | 0.73 | BCL6 (0.46) | BCL6MAPTGAANPC1RAB9A | |
| SCHEMBL5032373 | 0.72 | SMN1; SMN2 (0.39) | BCL6MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5037991 | 0.71 | BCL6 (0.37) | BCL6MAPTRAB9AMEN1KMT2A | |
| SCHEMBL4835516 | 0.71 | BCL6 (0.44) | BCL6MAPTGAANPC1RAB9A | |
| SCHEMBL5032431 | 0.71 | NPSR1 (0.38) | BCL6MAPTNPC1RAB9ALMNA | |
| SCHEMBL4832283 | 0.71 | MAPT (0.55) | BCL6MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |