Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032431 | 0.90 | NPSR1 (0.38) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL4836940 | 0.85 | EHMT2 (0.48) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL5032511 | 0.82 | RAB9A (0.39) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL5035185 | 0.80 | EGFR (0.38) | BCL6MAPK8 | |
| SCHEMBL5037991 | 0.80 | BCL6 (0.37) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL5037806 | 0.78 | BCL6 (0.36) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL5032257 | 0.77 | BCL6 (0.39) | MEN1MAPTKMT2ABCL6RAB9A | |
| SCHEMBL4837134 | 0.76 | DRD2 (0.49) | MAPTBLM | |
| Malonic Acid SCHEMBL4829481 | 0.76 | EHMT2 (0.45) | BCL6EHMT2EHMT1GALR2GALR1 | |
| SCHEMBL4838933 | 0.76 | EHMT2 (0.45) | SMN1; SMN2MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |