Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593684 | 0.84 | CYP1A2 (0.50) | KDM4EALDH1A1POLBMAPTNR4A2 | |
| SCHEMBL4376783 | 0.84 | POLB (0.61) | KDM4EALDH1A1GAAHPGDPOLB | |
| SCHEMBL15054414 | 0.81 | MPO (0.46) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL3267043 | 0.81 | MPO (0.46) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL5397578 | 0.81 | POLB (0.41) | POLBMAPTNR4A2CYP1A2L3MBTL1 | |
| SCHEMBL11690458 | 0.81 | NQO2 (0.53) | KDM4EPOLBTSHRCASP1NR4A2 | |
| SCHEMBL4744795 | 0.81 | POLB (0.68) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL9073054 | 0.81 | MAPT (0.56) | KDM4EALDH1A1GAAHPGDPOLB | |
| Bromide SCHEMBL9069438 | 0.79 | MAPT (0.54) | KDM4EALDH1A1GAAHPGDPOLB | |
| SCHEMBL12708309 | 0.78 | HSD17B10 (0.46) | KDM4EALDH1A1GAAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010749-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20230062748-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2023-03-02 | — | — | US | disclosed |
| CN-115485313-A | Improver for polyesters for improving melt viscosity | 钟化美洲控股公司 | 2022-12-16 | — | — | CN | disclosed |
| WO-2021159009-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-2427434-B1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-1395564-B1 | QUINOLINE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y RECEPTOR | HOFFMANN LA ROCHE (CH) | 2008-02-27 | — | — | EP | disclosed |
| US-20050049413-A1 | Quinoline derivatives | MUELLER WERNER (CH) | 2005-03-03 | — | — | US | disclosed |
| US-6818767-B2 | NEUROPEPTIDE Y (NPY) ANTAGONISTS FOR THE TREATMENT OR PREVENTION OF ARTHRITIS, CARDIOVASCULAR DISEASES, DIABETES, RENAL FAILURE, EATING DISORDERS, OR OBESITY | HOFFMANN-LA ROCHE INC. | 2004-11-16 | — | — | US | disclosed |
| US-20020198194-A1 | Quinoline derivatives | HOFFMANN-LA ROCHE INC. | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198194-A1 | Quinoline derivatives | NPY2R, NPY1R, NPY4R | KDM4E 1210/4885ALDH1A1 4803/4885GAA 826/4885 |
| US-20050049413-A1 | Quinoline derivatives | NPY2R, NPY1R, NPY4R | KDM4E 1210/4885ALDH1A1 4803/4885GAA 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.