Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465780 | 0.80 | — | — | |
| SCHEMBL1820120 | 0.79 | HDAC8 (0.58) | HDAC8LMNAMAPTMEN1KMT2A | |
| SCHEMBL1649302 | 0.76 | HDAC8 (0.55) | HDAC8LMNAMAPTGRM5FFAR1 | |
| Isonicotinonitrile SCHEMBL12264099 | 0.73 | — | — | |
| Isonicotinonitrile SCHEMBL2015834 | 0.73 | HDAC8 (0.52) | HDAC8LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL1190707 | 0.73 | HDAC8 (0.52) | HDAC8LMNAMAPTMEN1KMT2A | |
| SCHEMBL4583853 | 0.73 | — | — | |
| SCHEMBL446651 | 0.73 | — | — | |
| Isonicotinonitrile SCHEMBL151611 | 0.73 | — | — | |
| SCHEMBL11019406 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274419-A1 | Photoconductors | XEROX CORPORATION | 2008-11-06 | — | — | US | claimed |
| US-20080274419-A1 | Photoconductors | XEROX CORPORATION | 2008-11-06 | — | — | US | disclosed |