SCHEMBL5033527

SCHEMBL5033527

CCCCC=Cc1ccccc1CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.43
CYSLTR2 Q9NS75 2/20 0.43
CYSLTR1 Q9Y271 2/20 0.43
BID P55957 3/20 0.39
BCL2L1 Q07817 3/20 0.39
MCL1 Q07820 3/20 0.39
BAK1 Q16611 3/20 0.39
OXER1 Q8TDS5 1/20 0.36
TLR8 Q9NR97 1/20 0.36
MMP2 P08253 2/20 0.36
F7 P08709 2/20 0.36
F3 P13726 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 2/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27892530 0.87 BID (0.41) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL9802035 0.84 LIPG (0.49) CYSLTR2CYSLTR1BIDBCL2L1MCL1
SCHEMBL9802025 0.84 LIPG (0.49) CYSLTR2CYSLTR1BIDBCL2L1MCL1
SCHEMBL3269456 0.84 PDE5A (0.50) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL27876083 0.82 F7 (0.47) CYSLTR2CYSLTR1BIDBCL2L1MCL1
SCHEMBL21383361 0.82 CYSLTR2 (0.36) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL21383033 0.82 CYSLTR2 (0.36) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL21383266 0.82 CYSLTR2 (0.36) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL3418372 0.81 CYSLTR2 (0.46) PDE5ACYSLTR2CYSLTR1BIDBCL2L1
SCHEMBL3418375 0.81 CYSLTR2 (0.46) PDE5ACYSLTR2CYSLTR1BIDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182677-A1 Curable Compositions AGC Multi Material America, Inc. 2024-06-06 US disclosed
CN-118047914-A Curable composition AGC多材料美国有限公司 2024-05-17 CN disclosed
CN-116940608-A Curable composition AGC多材料美国有限公司 2023-10-24 CN disclosed
WO-2023164430-A1 CURABLE COMPOSITIONS AGC Multi Material America, Inc. (US) 2023-08-31 WO disclosed
US-20230265275-A1 Curable Compositions AGC Multi Material America, Inc. 2023-08-24 US disclosed
US-7402645-B2 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-20070155923-A1 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed
US-6900273-B1 Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part HITACHI CHEMICAL CO., LTD. (JP) 2005-05-31 US disclosed
US-20040220342-A1 Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part YAMASHITA YUKIHIKO (JP) 2004-11-04 US disclosed
EP-1205517-A1 LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-05-15 EP disclosed