Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151135 | 0.83 | CYP3A4 (0.36) | CYP3A4ACHEKDM4EKMT2A | |
| SCHEMBL16652323 | 0.80 | ACHE (0.40) | CYP3A4ACHE | |
| SCHEMBL8775679 | 0.79 | CYP3A4 (0.36) | CYP3A4ACHE | |
| SCHEMBL29847388 | 0.78 | KDM4E (0.32) | KDM4EKMT2A | |
| SCHEMBL5035156 | 0.77 | — | — | |
| SCHEMBL16906273 | 0.71 | CYP3A4 (0.33) | CYP3A4ACHEKDM4EKMT2A | |
| SCHEMBL30856622 | 0.70 | — | — | |
| SCHEMBL31283424 | 0.68 | KDM4E (0.32) | KDM4EKMT2A | |
| SCHEMBL6115021 | 0.68 | CHRM2 (0.35) | KDM4EKMT2A | |
| SCHEMBL5640241 | 0.67 | CHRM2 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926730-A1 | NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | AstraZeneca AB (SE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007030061-A1 | NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2007-03-15 | — | — | WO | disclosed |