Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038572 | 1.00 | POLB (0.47) | POLBALDH1A1TRPA1CA12CA1 | |
| SCHEMBL17953209 | 0.77 | CA14 (0.30) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL27373538 | 0.76 | POLB (0.38) | POLBALDH1A1TRPA1CA12CA1 | |
| SCHEMBL2436938 | 0.76 | POLB (0.42) | POLBALDH1A1TRPA1HSD17B10LMNA | |
| SCHEMBL1621178 | 0.76 | ALDH1A1 (0.42) | POLBALDH1A1TRPA1CA12CA1 | |
| SCHEMBL5771 | 0.76 | ALDH1A1 (0.42) | POLBALDH1A1TRPA1CA12CA1 | |
| SCHEMBL2015431 | 0.76 | ALDH1A1 (0.42) | POLBALDH1A1TRPA1CA12CA1 | |
| SCHEMBL324716 | 0.75 | POLB (0.38) | POLBALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL324715 | 0.75 | POLB (0.38) | POLBALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL701746 | 0.75 | POLB (0.38) | POLBALDH1A1HSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | 7TM PHARMA A/S (DK) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | HRH2, HRH1, HRH3 | POLB 3736/4885ALDH1A1 1905/4885TRPA1 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.