Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535558 | 0.83 | SMN1; SMN2 (0.40) | KCNN4NPSR1MAPK1TSHRL3MBTL1 | |
| SCHEMBL247425 | 0.83 | SMN1; SMN2 (0.40) | KCNN4NPSR1MAPK1TSHRL3MBTL1 | |
| SCHEMBL11894382 | 0.83 | SMN1; SMN2 (0.40) | KCNN4NPSR1MAPK1TSHRL3MBTL1 | |
| SCHEMBL15602074 | 0.79 | KCNN4 (0.44) | KCNN4NPSR1HPGDMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16059704 | 0.78 | KCNN4 (0.42) | KCNN4NPSR1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL246691 | 0.75 | NOTUM (0.35) | KCNN4NPSR1TSHRLMNASMN1; SMN2 | |
| SCHEMBL28919323 | 0.72 | HSD17B1 (0.38) | NPSR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28918682 | 0.71 | MEN1 (0.40) | L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18022983 | 0.70 | KCNH2 (0.35) | — | |
| SCHEMBL22062248 | 0.70 | KCNN4 (0.41) | KCNN4NPSR1HPGDTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062751-A1 | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | Janssen Pharmaceuticals, Inc. (US) | 2012-05-18 | — | — | WO | disclosed |