SCHEMBL5034189

SCHEMBL5034189

CCCC[Si](Cl)(Cl)C1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CNR1 P21554 3/20 0.34
CNR2 P34972 3/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32
NAAA Q02083 1/20 0.32
EPHX1 P07099 9/20 0.31
EPHX2 P34913 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029823 0.98 CYP1A2 (0.41) CYP1A2CNR1CNR2MEN1KMT2A
SCHEMBL11314579 0.91 CYP1A2 (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11314580 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11315988 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11320698 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11320513 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11316742 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11309915 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11320652 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1
SCHEMBL11311204 0.90 NAAA (0.40) CYP1A2CNR1CNR2NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed