Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036782 | 0.87 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5037325 | 0.84 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5038587 | 0.79 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5043776 | 0.79 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5043687 | 0.78 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5034263 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL8356279 | 0.77 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5037630 | 0.77 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL3048071 | 0.77 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL3053296 | 0.76 | ADORA2A (0.76) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450796-B1 | BENZOTHIAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-04-09 | — | — | EP | claimed |