Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707280 | 0.87 | GHSR (0.53) | GHSREPHX2 | |
| SCHEMBL1425219 | 0.87 | GHSR (0.53) | GHSREPHX2 | |
| SCHEMBL5416762 | 0.85 | GHSR (0.52) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL2813574 | 0.82 | GHSR (0.63) | GHSREPHX2CA12CA1CA7 | |
| SCHEMBL29715495 | 0.82 | GHSR (0.63) | GHSREPHX2CA12CA1CA7 | |
| SCHEMBL18614234 | 0.82 | GHSR (0.63) | GHSREPHX2CA12CA1CA7 | |
| SCHEMBL16350191 | 0.80 | GHSR (0.46) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL5404964 | 0.80 | GHSR (0.47) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL16462945 | 0.80 | GHSR (0.50) | GHSREPHX2DPP8DPP9CA12 | |
| SCHEMBL5196233 | 0.80 | GHSR (0.61) | GHSREPHX2DPP8DPP9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101665-A1 | MACROCYCLIC COMPOUNDS AS HCV NS3 PROTEASE INHIBITORS | NOVARTIS AG (CH) | 2008-08-28 | — | — | WO | disclosed |
| EP-1896086-A1 | HYDRAZIDE CONJUGATES AS IMAGING AGENTS | Bristol-Myers Squibb Pharma Company (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007005491-A1 | HYDRAZIDE CONJUGATES AS IMAGING AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-01-11 | — | — | WO | disclosed |