Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034108 | 1.00 | ADORA3 (0.70) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5034551 | 0.99 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5031749 | 0.88 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3423089 | 0.84 | ADORA2A (0.68) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5032129 | 0.83 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL999074 | 0.82 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL999075 | 0.82 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3952630 | 0.82 | ADORA2A (0.76) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5033794 | 0.82 | ADORA2A (0.76) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4803658 | 0.81 | ADORA2A (0.75) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | claimed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | claimed |
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |