Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.45 |
| ▸ | NOS1 | P29475 | 9/20 | 0.45 |
| ▸ | NOS3 | P29474 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134847 | 0.84 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL4148356 | 0.80 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5034557 | 0.80 | NOS2 (0.48) | NOS2NOS1NOS3CYP2C9 | |
| SCHEMBL4153385 | 0.80 | NOS2 (0.46) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5033966 | 0.80 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL2830907 | 0.79 | NOS2 (0.47) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036430 | 0.79 | NOS2 (0.53) | NOS2NOS1NOS3CYP2C9 | |
| SCHEMBL5041160 | 0.78 | NOS2 (0.58) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5033993 | 0.78 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL2834784 | 0.78 | NOS2 (0.42) | NOS2NOS1NOS3CYP2C9FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670796-B1 | IMIDAZOPYRIDINE-DERIVATIVES AS INDUCIBLE NO-SYNTHASE INHIBITORS | NYCOMED GMBH (DE) | 2008-06-25 | — | — | EP | claimed |