Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034649 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL1415250 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL6552621 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL3110380 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL28573346 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL17574533 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL15043860 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL5678519 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL5678522 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL1004375 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954132-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007100758-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-09-07 | — | — | WO | claimed |