Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686368 | 0.94 | SIGMAR1 (0.44) | POLBALDH1A1KDM4ESIGMAR1LMNA | |
| SCHEMBL6680534 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL11545835 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL5214468 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL282600 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL6683678 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL28560209 | 0.92 | HTR2A (0.45) | POLBALDH1A1SIGMAR1HTR2AOPRM1 | |
| SCHEMBL3477567 | 0.86 | AOC3 (0.46) | SIGMAR1LMNAHTR2AHRH1AOC3 | |
| SCHEMBL15144138 | 0.86 | HRH1 (0.44) | SIGMAR1LMNAHTR2AHRH1 | |
| SCHEMBL31190174 | 0.81 | HRH1 (0.46) | LMNAHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218804-A | A kind of 4- alkylthio groups -3- isoxazolidinones derivative and its synthetic method | 中国科学院大连化学物理研究所 | 2018-06-29 | — | — | CN | claimed |
| CN-108147984-A | 3,3- dioxanes sulphur -2- alkoxy -2- propylene -1- ketone derivatives and its synthesis | 中国科学院大连化学物理研究所 | 2018-06-12 | — | — | CN | claimed |
| CN-104588100-B | Catalyst for catalyzing thioether oxidation as well as preparation method and application of catalyst | 福州大学 | 2017-05-10 | — | — | CN | claimed |
| EP-4056742-B1 | FIBERS, FIBER MULTILAYER STRUCTURE, SPINNING SOLUTION FOR ELECTROSPINNING, AND METHOD FOR PRODUCING FIBERS | SHINETSU CHEMICAL CO (JP) | 2026-04-15 | — | — | EP | disclosed |
| EP-3441508-B1 | SILICONE-MODIFIED POLYURETHANE FIBER AND METHOD FOR MANUFACTURING SAME | SHINETSU CHEMICAL CO (JP) | 2025-06-04 | — | — | EP | disclosed |
| EP-3279373-B1 | SILICONE-MODIFIED POLYURETHANE-BASED FIBER AND METHOD FOR MANUFACTURING SAME | SHINETSU CHEMICAL CO (JP) | 2024-03-06 | — | — | EP | disclosed |
| CN-116946989-A | Preparation method of phosphane/deuterated phosphane and derivatives thereof | 北京大学 | 2023-10-27 | — | — | CN | disclosed |
| US-20220403097-A1 | FIBERS, FIBER MULTILAYER STRUCTURE, SPINNING SOLUTION FOR ELECTROSPINNING, AND METHOD FOR PRODUCING FIBERS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4056742-A1 | FIBERS, FIBER MULTILAYER STRUCTURE, SPINNING SOLUTION FOR ELECTROSPINNING, AND METHOD FOR PRODUCING FIBERS | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-09-14 | — | — | EP | disclosed |
| US-20220169779-A1 | MATERIAL FOR MEDICAL USE AND METHOD FOR PRODUCING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| US-11174335-B2 | Silicone-modified polyurethane fiber and method for manufacturing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| EP-1667982-A4 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007123732-A2 | ANTIFUNGAL AND ANTIPARASITIC INDOLOQUINOLINE DERIVATIVES | FLORIDA A & M UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| EP-1667982-A2 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030791-A2 | ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0790974-A1 | SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS | Bayer Corporation (US) | 1997-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | IDO1, IDO2, NQO2 | POLB 3128/4885ALDH1A1 2731/4885KDM4E 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.