Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432655 | 0.84 | CA1 (0.30) | CA1CA2TDP1 | |
| SCHEMBL17772988 | 0.80 | GABRR1 (0.32) | TDP1 | |
| SCHEMBL19432853 | 0.80 | — | — | |
| SCHEMBL572461 | 0.80 | — | — | |
| SCHEMBL8976186 | 0.79 | ANPEP (0.31) | CA1CA2 | |
| SCHEMBL25657495 | 0.78 | CHRM1 (0.33) | CA2TDP1USP2TSHR | |
| SCHEMBL19286939 | 0.78 | CA1 (0.37) | CA1CA2 | |
| SCHEMBL11890791 | 0.78 | USP2 (0.31) | TDP1USP2TSHR | |
| SCHEMBL24072255 | 0.76 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL22215230 | 0.74 | CA1 (0.34) | CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |
| US-9968589-B2 | Method of treating disease by auricular anesthesia of cranial nerves | CREWS THOMAS M (US) | 2018-05-15 | — | — | US | disclosed |