Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034972 | 0.76 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL18727480 | 0.71 | — | — | |
| SCHEMBL19432853 | 0.71 | — | — | |
| SCHEMBL572461 | 0.71 | — | — | |
| SCHEMBL24515014 | 0.69 | SLC2A1 (0.32) | — | |
| SCHEMBL22912887 | 0.68 | USP2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22607233 | 0.67 | ACE2 (0.41) | CA1CA2 | |
| SCHEMBL10139549 | 0.67 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL15809588 | 0.67 | MAPT (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28201654 | 0.67 | CA1 (0.41) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |