Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 0.38 |
| ▸ | CES1 | P23141 | 11/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395946 | 1.00 | CES2 (0.38) | CES2CES1ALDH1A1EGFRPTPN1 | |
| SCHEMBL31038964 | 0.86 | CES2 (0.39) | CES2CES1ALDH1A1EGFRPDE4A | |
| SCHEMBL5866820 | 0.79 | CES2 (0.36) | CES2CES1ALDH1A1EGFRPDE4A | |
| Benzil SCHEMBL28453926 | 0.78 | CES2 (0.58) | CES2CES1ALDH1A1PDE4ALMNA | |
| Benzil SCHEMBL2341683 | 0.78 | CES2 (0.58) | CES2CES1ALDH1A1PDE4ALMNA | |
| SCHEMBL28758743 | 0.77 | CES2 (0.40) | CES2CES1ALDH1A1EGFRLMNA | |
| SCHEMBL28205998 | 0.76 | CES1 (0.38) | CES2CES1ALDH1A1EGFRLMNA | |
| SCHEMBL10775308 | 0.75 | CES2 (0.37) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL16210771 | 0.75 | CES1 (0.39) | CES2CES1ALDH1A1PDE4ALMNA | |
| SCHEMBL28821597 | 0.75 | CES1 (0.39) | CES2CES1ALDH1A1PDE4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421100-B1 | CHEMICAL SYNTHESIS OF SOLAMARGINE | GLYCOMED SCIENCES LTD (KY) | 2008-07-09 | — | — | EP | disclosed |
| US-20040259814-A1 | Synthesis of solanum glycosides | GLYCOMED SCIENCES LIMITED (KY) | 2004-12-23 | — | — | US | disclosed |
| EP-1421100-A1 | CHEMICAL SYNTHESIS OF SOLAMARGINE | GlycoMed Sciences Limited (AU) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003018604-A1 | SYNTHESIS OF SOLANUM GLYCOSIDES | GLYCOMED SCIENCES LIMITED (AU) | 2003-03-06 | — | — | WO | disclosed |
| EP-0721956-B1 | 21-SUBSTITUTED STEROID COMPOUND | NISSIN FOOD PRODUCTS LTD (JP) | 2000-08-02 | — | — | EP | disclosed |
| EP-0721956-A1 | 21-SUBSTITUTED STEROID COMPOUND | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1996-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259814-A1 | Synthesis of solanum glycosides | GALE, MGAM, STS | CES2 2084/4885CES1 1806/4885ALDH1A1 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.