Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503526 | 1.00 | BLM (0.67) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL540243 | 1.00 | BLM (0.67) | BLMESR1ESR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL540242 | 0.98 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL540244 | 0.98 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1322060 | 0.98 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL180210 | 0.85 | BLM (0.47) | BLMMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL3647847 | 0.85 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A | |
| SCHEMBL31195654 | 0.85 | BLM (0.47) | BLMMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL180265 | 0.85 | BLM (0.47) | BLMMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL4610735 | 0.85 | BLM (0.65) | BLMESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445678-B2 | 2-quinoxalinol salen compounds and uses thereof | AUBURN UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | AUBURN UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | AUBURN UNIVERSITY (US) | 2009-11-19 | — | — | US | disclosed |
| CN-1211232-A | Benzamidine derivatives substituted with amino acid and hydroxy acid derivatives and their use as anticoagulants | BERLEX LAB (US) | 1999-03-17 | — | — | CN | disclosed |
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | NQO1, NQO2, SQOR | BLM 309/4885ESR1 3533/4885ESR2 3229/4885 |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | NQO1, NQO2, SQOR | BLM 309/4885ESR1 3533/4885ESR2 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.