Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 15/20 | 0.83 |
| ▸ | BCHE | P06276 | 5/20 | 0.83 |
| ▸ | ACHE | P22303 | 5/20 | 0.83 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.83 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.83 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.83 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.83 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.83 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.83 |
| ▸ | RECQL | P46063 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | THPO | P40225 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913173 | 1.00 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918181 | 1.00 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918396 | 0.98 | CHRM2 (0.79) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918881 | 0.91 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918894 | 0.91 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918374 | 0.91 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL31138865 | 0.91 | CHRM2 (0.93) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL11982296 | 0.91 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL29456771 | 0.91 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL5695121 | 0.90 | ALDH1A1 (0.79) | CHRM2BCHEACHECHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914254-B1 | Crosslinkers for improving stability of polyurethane foams | EVONIK DEGUSSA GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |