Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302954 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8572239 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8573097 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8576746 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL511473 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL719958 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7609467 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL16778332 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL8574509 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL27082991 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | claimed |
| WO-2007116149-A1 | NOVEL STRONTIUM SALTS OF SULFONIC ACIDS, PROCESS FOR PREPARING THEM AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-10-18 | — | — | WO | claimed |
| EP-1845082-A1 | New strontium salts of sulphonic acids, preparation method and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2007-10-17 | — | — | EP | claimed |
| EP-0124233-B1 | 21-HYDROXYCORTICOSTEROID ESTERS, AND COMPOSITIONS CONTAINING THEM | THE UPJOHN COMPANY (US) | 1989-09-27 | — | — | EP | claimed |
| US-10265693-B2 | Particles, particle dispersion, particle-dispersed resin composition, producing method therefor, resin molded article, producing method therefor, catalyst particles, catalyst solution, catalyst composition, catalyst molded article, titanium complex, titanium oxide particles and producing method therefor | NITTO DENKO CORPORATION (JP) | 2019-04-23 | — | — | US | disclosed |
| US-9847544-B2 | Ion conductive organic-inorganic composite particles, particle-containing resin composition and ion conductive molded article | NITTO DENKO CORPORATION (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170189895-A1 | PARTICLES, PARTICLE DISPERSION, PARTICLE-DISPERSED RESIN COMPOSITION, PRODUCING METHOD THEREFOR, RESIN MOLDED ARTICLE, PRODUCING METHOD THEREFOR, CATALYST PARTICLES, CATALYST SOLUTION, CATALYST COMPOSITION, CATALYST MOLDED ARTICLE, TITANIUM COMPLEX, TITANIUM OXIDE PARTICLES AND PRODUCING METHOD THEREFOR | NITTO DENKO CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20160222194-A1 | PARTICLES, PARTICLE DISPERSION, PARTICLE-DISPERSED RESIN COMPOSITION, PRODUCING METHOD THEREFOR, RESIN MOLDED ARTICLE, PRODUCING METHOD THEREFOR, CATALYST PARTICLES, CATALYST SOLUTION, CATALYST COMPOSITION, CATALYST MOLDED ARTICLE, TITANIUM COMPLEX, TITANIUM OXIDE PARTICLES AND PRODUCING METHOD THEREFOR | NITTO DENKO CORPORATION (JP) | 2016-08-04 | — | — | US | disclosed |
| US-20150065340-A1 | PARTICLES, PARTICLE DISPERSION, PARTICLE-DISPERSED RESIN COMPOSITION, PRODUCING METHOD THEREFOR, RESIN MOLDED ARTICLE, PRODUCING METHOD THEREFOR, CATALYST PARTICLES, CATALYST SOLUTION, CATALYST COMPOSITION, CATALYST MOLDED ARTICLE, TITANIUM COMPLEX, TITANIUM OXIDE PARTICLES AND PRODUCING METHOD THEREFOR | NITTO DENKO CORPORATION (JP) | 2015-03-05 | — | — | US | disclosed |
| CN-104053462-A | SEPARATION MATERIAL COMPRISING SACCHARIDE LIGANDS | GAMBRO LUNDIA AB | 2014-09-17 | — | — | CN | disclosed |
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-8642778-B2 | Ionic liquids | MERCK PATENT GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| US-20070010669-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2007-01-11 | — | — | US | disclosed |
| US-20070010669-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2007-01-11 | — | — | US | disclosed |
| US-20070010536-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-01-11 | — | — | US | disclosed |
| US-20070010536-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-01-11 | — | — | US | disclosed |
| EP-0339506-A1 | Oral osmotic system with a modified adhesion of the membrane to the core | CIBA-GEIGY AG (CH) | 1989-11-02 | — | — | EP | disclosed |
| EP-0124233-B1 | 21-HYDROXYCORTICOSTEROID ESTERS, AND COMPOSITIONS CONTAINING THEM | THE UPJOHN COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0124233-A2 | 21-Hydroxycorticosteroid esters, and compositions containing them | THE UPJOHN COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4469689-A | WATER SOLUBLE, ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010669-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | ACIN1, HDAC3, HDAC1 | TSHR 1095/4885LMNA 1008/4885NFKB1 1378/4885 |
| US-20070010536-A1 | Novel class of cytodifferentiating agents and histone deacetylase inhibitors, and methods of use thereof | ACIN1, HDAC3, HDAC1 | TSHR 1095/4885LMNA 1008/4885NFKB1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.