SCHEMBL50366

SCHEMBL50366

O=C(O)C(=O)CP(=O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
TSHR P16473 1/20 0.58
BLM P54132 1/20 0.58
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ENO1 P06733 1/20 0.43
PGK1 P00558 1/20 0.43
PGK2 P07205 1/20 0.43
OR51E2 Q9H255 2/20 0.40
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MMP2 P08253 1/20 0.37
THRB P10828 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ACE P12821 1/20 0.36
SLC13A3 Q8WWT9 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
PEPD P12955 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19697647 0.77 TSHR (0.39) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL15612 0.73
Fosfonet SCHEMBL2801407 0.71
Fosfonet SCHEMBL26676053 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL26676054 0.71
Fosfonet SCHEMBL15510455 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL4607410 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL9162319 0.71
Fosfonet SCHEMBL11026013 0.71
Fosfonet SCHEMBL28151124 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-09-11 US claimed
EP-4605521-A2 GENETICALLY MODIFIED HOST CELLS PRODUCING L-SERINE CysBio ApS (DK) 2025-08-27 EP claimed
US-20250215468-A1 METHOD FOR CONVERTING CARBON SOURCE INTO SERINE NAN YA PLASTICS CORPORATION (TW) 2025-07-03 US claimed
WO-2025104134-A9 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-06-19 WO claimed
WO-2025104134-A2 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-05-22 WO claimed
EP-4556561-A1 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CysBio ApS (DK) 2025-05-21 EP claimed
CN-120005781-A Expression of biomolecules with improved promoters and TIR 赛斯生物私人有限公司 2025-05-16 CN claimed
US-20240391961-A1 AUTONOMOUS ORGANISMS FOR SYNTHESIS OF PERMANENTLY PHOSPHORYLATED PROTEINS OREGON STATE UNIVERSITY (US) 2024-11-28 US claimed
CN-118834862-A Method for synthesizing phosphonoacetaldehyde by enzymatic method 中国科学院大学 2024-10-25 CN claimed
CN-118725325-A Method for improving freezing resistance of metal-organic framework and application of method in erythrocyte freezing protection 华南理工大学 2024-10-01 CN claimed
US-8494779-B2 Method for screening essential metabolites in growth of microorganisms KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
US-20130109067-A1 METHOD FOR THE PREPARATION OF HYDROXY ACIDS METABOLIC EXPLORER 2013-05-02 US claimed
US-20110244575-A1 METHODS, SYSTEMS AND COMPOSITIONS FOR INCREASED MICROORGANISM TOLERANCE TO AND PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) OPX BIOTECHNOLOGIES, INC. 2011-10-06 US claimed
US-20100143911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-10 US claimed
CN-101611312-A Method for screening essential metabolites in microbial growth KOREA INST SCI & TECH (KR) 2009-12-23 CN claimed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 EP claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
EP-0258290-A1 METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD VORA, Shobhana (US) 1988-03-09 EP claimed
WO-1987004072-A1 METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD VORA SHOBHANA (US) 1987-07-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS CHAMP1, PHOSPHO1, RIOX2 MEN1 1665/4885LMNA 1915/4885HPGD 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.