SCHEMBL50366

SCHEMBL50366

O=C(O)C(=O)CP(=O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ TSHR P16473 1/20 0.58
▸ BLM P54132 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ TDP1 Q9NUW8 1/20 0.58
▸ ENO1 P06733 1/20 0.43
▸ PGK1 P00558 1/20 0.43
▸ PGK2 P07205 1/20 0.43
▸ OR51E2 Q9H255 2/20 0.40
▸ MAPK1 P28482 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MMP2 P08253 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ ACE P12821 1/20 0.36
▸ SLC13A3 Q8WWT9 1/20 0.36
▸ EGLN1 Q9GZT9 1/20 0.36
▸ PEPD P12955 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19697647 0.77 TSHR (0.39) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL15612 0.73 — —
Fosfonet SCHEMBL15510455 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL11026013 0.71 — —
Fosfonet SCHEMBL26676054 0.71 — —
Fosfonet SCHEMBL2801407 0.71 — —
Fosfonet SCHEMBL9162319 0.71 — —
Fosfonet SCHEMBL26676053 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL4607410 0.71 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL28151124 0.71 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-09-11 — — US claimed
EP-4605521-A2 GENETICALLY MODIFIED HOST CELLS PRODUCING L-SERINE CysBio ApS (DK) 2025-08-27 — — EP claimed
US-20250215468-A1 METHOD FOR CONVERTING CARBON SOURCE INTO SERINE NAN YA PLASTICS CORPORATION (TW) 2025-07-03 — — US claimed
WO-2025104134-A9 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-06-19 — — WO claimed
WO-2025104134-A2 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-05-22 — — WO claimed
EP-4556561-A1 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CysBio ApS (DK) 2025-05-21 — — EP claimed
CN-120005781-A Expression of biomolecules with improved promoters and TIR 赛斯生物私人有限公司 2025-05-16 — — CN claimed
US-20240391961-A1 AUTONOMOUS ORGANISMS FOR SYNTHESIS OF PERMANENTLY PHOSPHORYLATED PROTEINS OREGON STATE UNIVERSITY (US) 2024-11-28 — — US claimed
CN-118834862-A Method for synthesizing phosphonoacetaldehyde by enzymatic method 中国科学院大学 2024-10-25 — — CN claimed
CN-118725325-A Method for improving freezing resistance of metal-organic framework and application of method in erythrocyte freezing protection 华南理工大学 2024-10-01 — — CN claimed
US-8494779-B2 Method for screening essential metabolites in growth of microorganisms KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 — — US claimed
US-20130109067-A1 METHOD FOR THE PREPARATION OF HYDROXY ACIDS METABOLIC EXPLORER 2013-05-02 — — US claimed
US-20110244575-A1 METHODS, SYSTEMS AND COMPOSITIONS FOR INCREASED MICROORGANISM TOLERANCE TO AND PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) OPX BIOTECHNOLOGIES, INC. 2011-10-06 — — US claimed
US-20100143911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-10 — — US claimed
CN-101611312-A Method for screening essential metabolites in microbial growth KOREA INST SCI & TECH (KR) 2009-12-23 — — CN claimed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 — — EP claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 — — WO claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 — — WO claimed
EP-0258290-A1 METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD VORA, Shobhana (US) 1988-03-09 — — EP claimed
WO-1987004072-A1 METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD VORA SHOBHANA (US) 1987-07-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282802-A1 PHOSPHONATE PRODUCTS AND METHODS CHAMP1, PHOSPHO1, RIOX2 MEN1 1665/4885LMNA 1915/4885HPGD 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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