SCHEMBL50368

SCHEMBL50368

CC1(C)CC(CN)C(C)(C)N1[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941187 0.83
SCHEMBL2992832 0.78 ADORA3 (0.36)
SCHEMBL9344255 0.78
SCHEMBL15003162 0.76
SCHEMBL6558986 0.75 ADORA3 (0.32)
SCHEMBL1932618 0.74 GAA (0.50)
SCHEMBL632418 0.71
SCHEMBL377189 0.70 GAA (0.30)
SCHEMBL16561780 0.69
SCHEMBL16013160 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4100010-B1 NITROXIDE COMPOUNDS FOR USE IN THE TREATMENT OF OPIOID-INDUCED RESPIRATORY DEPRESSION (OIRD) UNIV CASE WESTERN RESERVE (US) 2026-01-07 EP claimed
US-20250041285-A1 MODIFYING THE EXPRESSION LEVEL OF A GENE ENCODING AN CYCLOOXYGENASE ENZYME BY TREATING A HUMAN SUBJECT WITH A NITROXIDE HABASH LOUIS (US) 2025-02-06 US claimed
US-12208089-B2 Adjusting expression level of a gene encoding a Sirtuin protein by treating a human subject with a nitroxide HABASH LOUIS (US) 2025-01-28 US claimed
US-20240415826-A1 MODULATING EXPRESSION LEVEL OF A GENE ENCODING AN UNCOUPLING PROTEIN BY TREATING A HUMAN SUBJECT WITH A NITROXIDE HABASH LOUIS (US) 2024-12-19 US claimed
US-11998536-B2 Decreasing expression level of proteasome subunit genes by treating a human subject with a nitroxide HABASH LOUIS (US) 2024-06-04 US claimed
EP-3458522-B1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY ICROM SPA (IT) 2024-01-03 EP claimed
US-11819500-B2 T-cell regulation in t-cell mediated diseases by reducing pathogenic function of TH17 in a human subject through treatment with a nitroxide HABASH LOUIS (US) 2023-11-21 US claimed
US-20230203091-A1 GLYCOCONJUGATION PROCESS PFIZER (US) 2023-06-29 US claimed
US-20230149442-A1 Biodegradable, Antioxidant, Thermally Responsive Injectable Hydrogel and Uses Therefor UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-05-18 US claimed
EP-4100010-A1 COMPOSITIONS AND METHODS FOR ATTENUATING OPIOID INDUCED CARDIO AND/OR RESPIRATORY DEPRESSION Case Western Reserve University (US) 2022-12-14 EP claimed
US-20080044611-A1 Pressure Sensitive Adhesive Tape for the Adhesion of Printing Plates and Method for the Production Thereof TESA AG (DE) 2008-02-21 US claimed
EP-1590383-A2 PRESSURE-SENSITIVE ADHESIVE TAPE FOR THE ADHESION OF PRINTING PLATES AND METHOD FOR THE PRODUCTION THEREOF Tesa AG (DE) 2005-11-02 EP claimed
WO-2004067661-A2 TWO-STAGE FREE-RADICAL POLYMERIZATION METHOD FOR THE PRODUCTION OF PRESSURE-SENSITIVE ADHESIVES FOR PRESSURE-SENSITIVE ADHESIVE TAPES USED FOR BONDING PRINTING PLATES TESA AG (DE) 2004-08-12 WO claimed
US-6677483-B2 DISSOLVING DIETHYLENETRIAMINEPENTAACETIC- BISANHYDRIDE OF FORMULA IN DIMETHYL SULFOXIDE OR IN DIMETHYLFORMAMIDE OR IN A MIXTURE; ADDING SOLUBILIZER, AN AUXILIARY BASE AND A MONOAMINE OR DIAMINE, HEATING SCHERING AG (DE) 2004-01-13 US claimed
US-20020155065-A1 Process for the production of monoamides of DTPA SCHERING AG (DE) 2002-10-24 US claimed
EP-1025263-A2 LABELLING OF POLYMERS AND SEQUENCING OF NUCLEIC ACIDS GUILLET, James Edwin (CA) 2000-08-09 EP claimed
WO-1999022020-A2 LABELLING OF POLYMERS AND SEQUENCING OF NUCLEIC ACIDS GUILLET JAMES E (CA) 1999-05-06 WO claimed
US-5714510-A Topical proxyl composition and method PROCTOR PETER H (US) 1998-02-03 US claimed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP claimed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed