Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446463 | 0.84 | CYP19A1 (0.41) | CYP19A1ALDH1A1MAPTSMN1; SMN2FNTA | |
| SCHEMBL1097299 | 0.81 | CYP19A1 (0.42) | CYP19A1ALDH1A1MAPTSMN1; SMN2FNTA | |
| SCHEMBL12820668 | 0.74 | CYP11B1 (0.58) | CYP19A1ALDH1A1MAPTSMN1; SMN2FNTA | |
| SCHEMBL1096475 | 0.73 | CYP19A1 (0.41) | CYP19A1ALDH1A1MAPTSMN1; SMN2FNTA | |
| SCHEMBL8441652 | 0.72 | CYP19A1 (0.49) | CYP19A1ALDH1A1MAPTSMN1; SMN2CYP11B1 | |
| SCHEMBL27855265 | 0.71 | CYP11B1 (0.48) | CYP19A1ALDH1A1MAPTSMN1; SMN2CYP11B1 | |
| SCHEMBL8359571 | 0.69 | CYP19A1 (0.46) | CYP19A1ALDH1A1MAPTSMN1; SMN2FNTA | |
| SCHEMBL27735977 | 0.68 | CYP19A1 (0.38) | CYP19A1ALDH1A1MAPTSMN1; SMN2CYP11B1 | |
| Hydrochloric Acid SCHEMBL7847528 | 0.68 | CYP19A1 (0.52) | CYP19A1ALDH1A1MAPTSMN1; SMN2CYP11B1 | |
| SCHEMBL1950222 | 0.67 | CYP11B1 (0.63) | CYP19A1ALDH1A1MAPTSMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001866-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007117982-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-18 | — | — | WO | disclosed |