Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838566 | 0.83 | CYP3A4 (0.44) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL692130 | 0.75 | MEN1 (0.39) | CYP19A1LMNAMEN1CYP2D6TSHR | |
| SCHEMBL8613849 | 0.75 | MEN1 (0.39) | CYP19A1LMNAMEN1CYP2D6TSHR | |
| SCHEMBL3719178 | 0.71 | ESR1 (0.48) | CYP3A4CYP2C19SLC6A2SLC6A3GAA | |
| SCHEMBL109077 | 0.71 | ESR1 (0.48) | CYP3A4CYP2C19SLC6A2SLC6A3GAA | |
| SCHEMBL6981619 | 0.71 | IDO1 (0.38) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL5031674 | 0.70 | SLC6A2 (0.42) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10280947 | 0.69 | CYP3A4 (0.36) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22611925 | 0.67 | CYP3A4 (0.48) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5145632 | 0.67 | CYP3A4 (0.39) | CYP3A4CYP2C19SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274419-A1 | Photoconductors | XEROX CORPORATION | 2008-11-06 | — | — | US | claimed |