SCHEMBL503727

SCHEMBL503727

CCCCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.96

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.96
TSHR P16473 1/20 0.96
PLA2G4B P0C869 8/20 0.93
RARB P10826 4/20 0.87
PLA2G4A P47712 1/20 0.82
HTT P42858 1/20 0.71
PLA2G2A P14555 1/20 0.67
PTPN11 Q06124 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503568 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL10778285 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL3625733 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL503352 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1163918 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL7470745 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1322922 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL10777726 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1469965 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL371494 0.98 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116136001-B Carboxylic acid extractant and method for separating impurity aluminum ions from rare earth feed liquid by using same 厦门稀土材料研究所 2024-12-24 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-116136001-A Carboxylic acid extractant and method for separating impurity aluminum ions from rare earth feed liquid by using same 厦门稀土材料研究所 2023-05-19 CN claimed
CN-112266781-A Thermochromic material composition 江苏康恒化工有限公司 2021-01-26 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-8216649-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-07-10 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
EP-0347963-B1 Thermotropic copolyester, process for preparing it and its use ENIRICERCHE SPA (IT) 1995-04-05 EP claimed
US-5086160-A Catalytically reacting a saturated aliphatic acid, a 4,4*-di-hydroxy-diphenyl or esters thereof ENIRICERCHE S.P.A. (IT) 1992-02-04 US claimed
EP-0175591-B1 LACTIC ACID DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed
EP-0347963-A2 Thermotropic copolyester, process for preparing it and its use ENIRICERCHE S.p.A. (IT) 1989-12-27 EP claimed
EP-0175591-A2 Lactic acid derivative, liquid crystal composition containing same and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1986-03-26 EP claimed
US-4515886-A PHOTORESISTS, SEMICONDUCTORS TOYO SODA MANUFACTURING CO., LTD. (JP) 1985-05-07 US claimed
US-4243740-A Light sensitive compositions of polymethyl isopropenyl ketone TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-01-06 US claimed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US claimed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS TP53 234/4885TSHR 1605/4885PLA2G4B 2095/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS TP53 234/4885TSHR 1605/4885PLA2G4B 2095/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS TP53 234/4885TSHR 1605/4885PLA2G4B 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.