SCHEMBL7470745

SCHEMBL7470745

CCCCCCCCCCCCCCOc1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 1.00
TSHR P16473 1/20 1.00
PLA2G4B P0C869 8/20 0.97
RARB P10826 4/20 0.90
PLA2G4A P47712 1/20 0.85
HTT P42858 1/20 0.73
PLA2G2A P14555 1/20 0.70
PTPN11 Q06124 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778285 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL371494 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL503568 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL10777726 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL3625733 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1163918 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1322922 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1469965 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL503352 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL503367 1.00 TP53 (1.00) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
US-9737612-B2 Antagonistic DR3 ligands NOVO NORDISK A/S (DK) 2017-08-22 US disclosed
US-9737612-B2 Antagonistic DR3 ligands NOVO NORDISK A/S (DK) 2017-08-22 US disclosed
EP-0817773-B1 PYRIMIDINE COMPOUNDS QINETIQ LTD (GB) 2002-06-12 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-6121448-A LIQUID CRYSTALLINE COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITTANIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2000-09-19 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5986096-A REACTION OF HYDROGEN IODIDE WITH CHLORO-5-BROMOPYRIMIDINE THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S A GOVERNMENT OF THE U.K. OF GT. BRITAIN & N. IRELAND OF DEFENCE EVALUATION & RESEARCH AGENCY (GB) 1999-11-16 US disclosed
US-4683244-A Sebosuppressive cosmetic preparations containing alkoxy or alkylbenzyloxy benzoic acids or their salts HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-07-28 US disclosed
US-4640913-A Phosphocholine derivatives having antihypertensive action AMERICAN CYANAMID COMPANY (US) 1987-02-03 US disclosed
EP-0208617-A1 Controlled drug device and process for catalysing the erosion of an acid labile polymer MERCK & CO. INC. (US) 1987-01-14 EP disclosed
EP-0191286-A2 Sebosuppressive cosmetic compositions containing alkoxy or alkylbenzyloxybenzoic acids or salts thereof Henkel Kommanditgesellschaft auf Aktien (DE) 1986-08-20 EP disclosed
EP-0188222-A2 Novel liquid cristalline compounds having substituents DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-07-23 EP disclosed
EP-0079913-B1 ARENE-CARBOXYLIC ACID DERIVATIVES USED AS AGENTS HAVING AN ANTI-SEBORRHEA EFFECT CONTAINED IN COSMETIC COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1986-02-26 EP disclosed
US-4192895-A SUBSTITUTED BENZALDEHYDES AND PHENYL ALKYL KETONES RICHARDSON-MERRELL INC. (US) 1980-03-11 US disclosed
US-4187319-A HYDROCARBYLTHIO-SUBSTITUTED RICHARDSON-MERRELL INC. (US) 1980-02-05 US disclosed
US-4122191-A SUBSTITUTED BENZALDEHYDES OR PHENYL ALKYL KETONES RICHARDSON-MERRELL INC. (US) 1978-10-24 US disclosed
US-4066788-A Substituted benzaldehyde hypolipidemic agents RICHARDSON-MERRELL INC. (US) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SLC6A9, SLC6A5, REN TP53 4795/4885TSHR 4030/4885PLA2G4B 2926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.