Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503750 | 0.80 | TSHR (0.32) | TSHR | |
| SCHEMBL27449266 | 0.77 | — | — | |
| SCHEMBL609665 | 0.77 | CA12 (0.34) | ALDH1A1TSHR | |
| SCHEMBL608238 | 0.75 | TSHR (0.41) | TSHRMEN1POLBKMT2A | |
| SCHEMBL609861 | 0.74 | MEN1 (0.31) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL509439 | 0.73 | — | — | |
| SCHEMBL503681 | 0.72 | — | — | |
| SCHEMBL19779395 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53 | |
| SCHEMBL3126692 | 0.69 | — | — | |
| SCHEMBL14466936 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151673-A1 | Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation | SHEARES VALERIE V (US) | 2002-10-17 | — | — | US | claimed |
| US-12378327-B2 | Method of making a silica/cellulose hybrid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2025-08-05 | — | — | US | disclosed |
| CN-114621375-B | Rubber with backbone and end-group functionalization | 固特异轮胎和橡胶公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11912798-B2 | Rubber with backbone and end-group functionalization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-02-27 | — | — | US | disclosed |
| CN-114621375-A | Rubber with main chain and end group functionalization | 固特异轮胎和橡胶公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220177610-A1 | RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION | MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT | 2022-06-09 | — | — | US | disclosed |
| CN-114591518-A | Process for preparing silica/cellulose mixtures | 固特异轮胎和橡胶公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20220169752-A1 | METHOD OF MAKING A SILICA/CELLULOSE HYBRID | THE GOODYEAR TIRE & RUBBER COMPANY | 2022-06-02 | — | — | US | disclosed |
| EP-3239183-B1 | MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER | SUMITOMO CHEMICAL CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-10118973-B2 | Modified conjugated diene polymer, and polymer composition containing said polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-11-06 | — | — | US | disclosed |
| US-6664328-B1 | Tire with tread comprised of filler and rubbery polymer comprised of repeat units derived from conjugated diolefin monomer and functionalized monomer of specified structural formula; low hysteresis, good compatibility with filler | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-6630552-B1 | Butadiene-styrene copolymers with heterocyclic amine compounds | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-10-07 | — | — | US | disclosed |
| US-6627721-B1 | Rubbery polymer comprised of comonomers of conjugated diene and styrene substited with N-heterocycle or sulfide; hoses, power transmission belts | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| US-6627722-B2 | Rubber comprising comonomers of conjugated diolefin and vinyllaromatic compound substituted with N-heterocycle; tire treads | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-09-30 | — | — | US | disclosed |
| US-20030134997-A1 | Functionalized elastomers | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-17 | — | — | US | disclosed |
| US-6583260-B2 | Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2003-06-24 | — | — | US | disclosed |
| US-6583260-B2 | Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2003-06-24 | — | — | US | disclosed |
| US-20020151673-A1 | Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation | SHEARES VALERIE V (US) | 2002-10-17 | — | — | US | disclosed |
| US-6344538-B1 | REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6344538-B1 | REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2002-02-05 | — | — | US | disclosed |