Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037404 | 1.00 | F10 (0.46) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5047444 | 0.99 | F10 (0.48) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5047435 | 0.99 | F10 (0.48) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5041692 | 0.91 | F10 (0.57) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5041686 | 0.91 | F10 (0.57) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5040595 | 0.88 | F2 (0.43) | F10F2PRSS1EPHX2PLAU | |
| Hydrochloric Acid SCHEMBL5040592 | 0.88 | F2 (0.43) | F10F2PRSS1EPHX2PLAU | |
| SCHEMBL5041486 | 0.85 | F10 (0.63) | F10F2PRSS1PLAUPLG | |
| SCHEMBL5041473 | 0.85 | F10 (0.63) | F10F2PRSS1PLAUPLG | |
| SCHEMBL5041146 | 0.85 | F2 (0.48) | F10F2PRSS1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |