Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30814796 | 0.83 | RECQL (0.37) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968082 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL4035594 | 0.79 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL1574379 | 0.78 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL23245696 | 0.78 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL25712548 | 0.78 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL29851508 | 0.77 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968002 | 0.77 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL29851796 | 0.77 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968058 | 0.76 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149981-B | Protein degradation targeting chimera for degrading androgen receptor | 苏州德亘生物医药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| EP-1957493-A1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS MONOAMINE REUPTAKE INHIBITORS | N.V. Organon (NL) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063071-A1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS MONOAMINE REUPTAKE INHIBITORS | N.V. ORGANON (NL) | 2007-06-07 | — | — | WO | disclosed |