SCHEMBL503777

SCHEMBL503777

CCCCCC/C=C(\O)O/C(O)=C/CCCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.54
TSHR P16473 2/20 0.42
TERT O14746 3/20 0.42
PTPN1 P18031 3/20 0.42
PPARG P37231 3/20 0.42
PPARD Q03181 3/20 0.42
PPARA Q07869 3/20 0.42
TOP1 P11387 3/20 0.42
MAPT P10636 2/20 0.42
BLM P54132 2/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28501671 1.00 EP300 (0.54) EP300TSHRTERTPTPN1PPARG
SCHEMBL75520 0.90 EP300 (0.41) EP300TSHRTERTPTPN1PPARG
SCHEMBL29012038 0.90 EP300 (0.41) EP300TSHRTERTPTPN1PPARG
SCHEMBL28984168 0.86 EP300 (0.55) EP300TERTPTPN1PPARGPPARD
SCHEMBL7164496 0.80 EP300 (0.48) EP300TSHRMAPTBLMHSD17B10
SCHEMBL7164494 0.80 EP300 (0.48) EP300TSHRMAPTBLMHSD17B10
SCHEMBL4631111 0.79 BACE1 (0.34) EP300TSHR
SCHEMBL3480750 0.79 BACE1 (0.34) EP300TSHR
SCHEMBL5437395 0.78 EP300 (0.56) EP300TSHRTERTPTPN1PPARG
SCHEMBL5437390 0.78 EP300 (0.56) EP300TSHRTERTPTPN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5514288-A Method of pretreating fabrics to impart soil release properties thereto using polymers of vinyl ethers BASF CORPORATION (US) 1996-05-07 US claimed
US-20120027884-A1 NANO-IMPRINTING RESIN STAMPER AND NANO-IMPRINTING APPARATUS USING THE SAME HITACHI HIGH-TECHNOLOGIES CORPORATION (JP) 2012-02-02 US disclosed
EP-0911152-B1 White laminated polyester film and imaging medium MITSUBISHI POLYESTER FILM CORP (JP) 2007-06-20 EP disclosed
US-6143408-A White laminated polyester film and imaging medium MITSUBISHI POLYESTER FILM CORPORATION (JP) 2000-11-07 US disclosed
EP-0911152-A2 White laminated polyester film and imaging medium Mitsubishi Polyester Film Corporation (JP) 1999-04-28 EP disclosed
US-5514288-A Method of pretreating fabrics to impart soil release properties thereto using polymers of vinyl ethers BASF CORPORATION (US) 1996-05-07 US disclosed