Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891011 | 1.00 | EP300 (0.56) | EP300TSHRTERTPTPN1PPARG | |
| SCHEMBL5437390 | 1.00 | EP300 (0.56) | EP300TSHRTERTPTPN1PPARG | |
| SCHEMBL13317211 | 0.97 | EP300 (0.52) | EP300TSHRTERTPTPN1PPARG | |
| SCHEMBL6034301 | 0.90 | — | — | |
| SCHEMBL21002254 | 0.90 | — | — | |
| SCHEMBL6034303 | 0.90 | — | — | |
| Allyl Alcohol SCHEMBL27689429 | 0.88 | TSHR (0.50) | EP300TSHRTERTPTPN1PPARG | |
| SCHEMBL6692740 | 0.83 | EP300 (0.54) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL833159 | 0.83 | EP300 (0.54) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL17199787 | 0.83 | EP300 (0.54) | EP300TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316577-A | GLi1 inhibitors as therapeutic agents | 纽约大学 | 2021-08-27 | — | — | CN | disclosed |
| WO-2013018929-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-07 | — | — | WO | disclosed |
| US-20070191649-A1 | Method for producing a propargyl alcohol and an allyl alcohol | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191649-A1 | Method for producing a propargyl alcohol and an allyl alcohol | ADH1A, ADH1C, AKR1C3 | EP300 444/4885TSHR 1777/4885TERT 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.