Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 5/20 | 0.39 |
| ▸ | NMT2 | O60551 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844633 | 0.84 | DPP8 (0.46) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL28792808 | 0.82 | GSR (0.50) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL5379254 | 0.82 | GSR (0.50) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL14343195 | 0.82 | GSR (0.50) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL3338905 | 0.82 | GSR (0.50) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL13496274 | 0.81 | ERAP2 (0.54) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL1065054 | 0.80 | GSR (0.52) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL7747523 | 0.80 | DPP7 (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL503847 | 0.80 | DPP7 (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL2734207 | 0.78 | ERAP2 (0.52) | DPP8DPP9DPP7GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642728-B2 | Modulation of the activity and differentiation of cells expressing the osteoclast-associated receptor | CAMBRIDGE ENTERPRISE LTD. (GB) | 2014-02-04 | — | — | US | disclosed |
| US-20130280273-A1 | Modulation of the Activity and Differentiation of Cells Expressing the Osteoclast-Associated Receptor | CAMBRIDGE ENTPR LTD (GB) | 2013-10-24 | — | — | US | disclosed |
| US-20120028903-A1 | MODULATION OF THE ACTIVITY AND DIFFERENTIATION OF CELLS EXPRESSING THE OSTEOCLAST-ASSOCIATED RECEPTOR | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2012-02-02 | — | — | US | disclosed |
| CN-102282169-A | Modulation of cellular activity and differentiation of osteoclast-associated receptors | — | 2011-12-14 | — | — | CN | disclosed |
| EP-2344530-A1 | MODULATION OF THE ACTIVITY AND DIFFERENTIATION OF CELLS EXPRESSING THE OSTEOCLAST-ASSOCIATED RECEPTOR | Cambridge Enterprise Limited (GB) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010040998-A1 | MODULATION OF THE ACTIVITY AND DIFFERENTIATION OF CELLS EXPRESSING THE OSTEOCLAST-ASSOCIATED RECEPTOR | CAMBRIDGE ENTERPRISE LLIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |
| WO-2007052067-A2 | VON WILLEBRAND FACTOR (VWF) BINDING PEPTIDES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007017671-A1 | COLLAGEN PEPTIDES, METHODS AND USES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |
| EP-1068313-A2 | COLLAGEN PEPTIDES AND USES THEREOF | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999050281-A2 | COLLAGEN PEPTIDES AND USES THEREOF | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 1999-10-07 | — | — | WO | disclosed |