Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13496274 | 0.84 | ERAP2 (0.54) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL503846 | 0.84 | DPP8 (0.43) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL7747523 | 0.83 | DPP7 (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL503847 | 0.83 | DPP7 (0.58) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL7570529 | 0.82 | DPP8 (0.51) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL2734207 | 0.82 | ERAP2 (0.52) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL2887132 | 0.80 | GSR (0.55) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL29462129 | 0.80 | DPP8 (0.49) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL29805332 | 0.80 | DPP8 (0.49) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL29740503 | 0.80 | DPP8 (0.49) | DPP8DPP9DPP7GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002465-A1 | Polyene macrolide derivatives, use for vectoring molecules | UNIVERSITE PIERRE ET MARIE CURIE (FR) | 2004-01-01 | — | — | US | disclosed |
| EP-1067969-B1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIV PARIS CURIE (FR) | 2003-07-23 | — | — | EP | disclosed |
| EP-1067969-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051274-A1 | POLYENE MACROLIDE DERIVATIVES, USE FOR VECTORING MOLECULES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 1999-10-14 | — | — | WO | disclosed |