Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chlorohippuric Acid SCHEMBL4002486 | 0.82 | KDM4E (0.67) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL6200322 | 0.82 | MEN1 (0.62) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL1913984 | 0.82 | KDM4E (0.72) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL11210009 | 0.82 | MEN1 (0.60) | CYP1A2TSHRNFKB1MAOBMAPT | |
| 4-Chlorohippuric Acid SCHEMBL11524882 | 0.82 | KDM4E (0.67) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL3363697 | 0.82 | CYP1A2 (0.63) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL11294257 | 0.81 | CYP1A2 (0.69) | CYP1A2TSHRNFKB1MAOBMAPT | |
| 4-Chlorohippuric Acid SCHEMBL11522704 | 0.81 | MAPT (0.65) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL11004530 | 0.81 | MEN1 (0.58) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL95020 | 0.81 | CA1 (0.50) | CYP1A2TSHRNFKB1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177348-A | Antineoplastic compound N-(2-(4-chlorophenyl)-5-oxazolyl)-2-(1,3-dioxo-2-isoindolinyl)acetamide synthesis method | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-12-03 | — | — | CN | disclosed |
| EP-1450796-B1 | BENZOTHIAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-04-09 | — | — | EP | disclosed |
| US-6596718-B1 | A compound of formula I has a good affinity to the A2A receptor and is useful for the treatment of diseases mediated by this receptor. | HOFFMANN-LA ROCHE INC. | 2003-07-22 | — | — | US | disclosed |
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |