Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203130 | 0.90 | KDM4E (0.53) | TSHRNFKB1MAPTKDM4EALDH1A1 | |
| SCHEMBL10674219 | 0.84 | MEN1 (0.51) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL13202996 | 0.84 | RAB9A (0.49) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| Acetic Acid SCHEMBL7506145 | 0.83 | CYP1A2 (0.56) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| 4-Chlorohippuric Acid SCHEMBL11524882 | 0.82 | KDM4E (0.67) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL6200322 | 0.82 | MEN1 (0.62) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL17299366 | 0.82 | KDM4E (0.67) | KMT2AMAPTKDM4ELMNA | |
| 4-Chlorohippuric Acid SCHEMBL4002486 | 0.82 | KDM4E (0.67) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL11210009 | 0.82 | MEN1 (0.60) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL5436981 | 0.82 | TDP1 (0.60) | KMT2AMAPTALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535089-A | Alkyloxazolylacetic acid derivative for the treatment of hyperlipidemia | TANABE SEIYAKU CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0094612-A2 | Novel alkyloxazolylacetic acid derivative, processes for preparation and pharmaceutical compositions containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |