Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.49 |
| ▸ | PDE4A | P27815 | 10/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038747 | 0.83 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL18971899 | 0.80 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29044734 | 0.77 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28163432 | 0.77 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7475124 | 0.77 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2954077 | 0.77 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2961023 | 0.77 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL833835 | 0.76 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL833836 | 0.76 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL5038816 | 0.75 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117943-A1 | 7-(3',4'-DIALKOXYPHENYL)-[1,2,4]-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS, PROCESS FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ARTHRITIS, ATOPIC DERMATITIS, TUMOR AND DEGENERATIVE BRAIN DISEASES COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-10-02 | — | — | WO | disclosed |