Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.57 |
| ▸ | PDE4A | P27815 | 10/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038816 | 0.89 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28163432 | 0.86 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL18971899 | 0.86 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2954077 | 0.86 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7475124 | 0.86 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29044734 | 0.86 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL5038747 | 0.83 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL8854690 | 0.82 | PDE4D (0.60) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7421380 | 0.82 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7418541 | 0.81 | PDE4A (0.52) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035349-A1 | 3,4-alkoxy Substituted Phenethyl Lactam Compound, Preparation Method therefor, and Use Thereof | GUANGZHOU CHIA TAI INNOVATIVE PHARMACEUTICAL CO., LTD. (CN) | 2026-02-05 | — | — | US | disclosed |
| CN-116535350-A | 3, 4-alkoxy substituted phenethyl lactam compound, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-08-04 | — | — | CN | disclosed |
| CN-103827088-B | It is used as the derivative of the pyridyl alkyl alcohol of 1 phenyl 2 of phosphodiesterase inhibitors | 奇斯药制品公司 | 2017-10-13 | — | — | CN | disclosed |
| US-9265768-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-02-23 | — | — | US | disclosed |
| EP-2760838-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2014-08-06 | — | — | EP | disclosed |
| CN-103827088-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2014-05-28 | — | — | CN | disclosed |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-05-22 | — | — | US | disclosed |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-05-22 | — | — | US | disclosed |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-05-22 | — | — | US | disclosed |
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |
| EP-1824854-A2 | SUBSTITUTED PTERIDINES FOR TREATING INFLAMMATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006058869-A2 | SUBSTITUTED PTERIDINES FOR TREATING INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |
| US-20060116373-A1 | Substituted pteridines for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-01 | — | — | US | disclosed |
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | disclosed |
| US-5811455-A | Compounds useful for treating allergic or inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |
| US-5449686-A | Compounds useful for treating allergic or inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0636025-A4 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0636025-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993019750-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993015044-A1 | N-BENZYLOXAMIC ACID, OXAMATE, AND OXAMIDE DERIVATIVES AND THEIR USE AS TNF AND PDE IV INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116373-A1 | Substituted pteridines for the treatment of inflammatory diseases | LTC4S, TLR5, LTB4R2 | PDE4B 1709/4885PDE4D 2722/4885PDE4A 1428/4885 |
| US-20260035349-A1 | 3,4-alkoxy Substituted Phenethyl Lactam Compound, Preparation Method therefor, and Use Thereof | CES1, CYP51A1, PDE3A | PDE4B 20/4885PDE4D 70/4885PDE4A 34/4885 |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE3A | PDE4B 2/4885PDE4D 8/4885PDE4A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.