Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176553 | 1.00 | ABL1 (0.39) | ABL1BCRJAK2JAK1TYK2 | |
| Formic Acid SCHEMBL5562238 | 0.96 | ABL1 (0.37) | ABL1BCRJAK2JAK1TYK2 | |
| SCHEMBL1175579 | 0.92 | DYRK1A (0.38) | ABL1BCRHSP90AA1HSP90AB1GSK3B | |
| SCHEMBL5044466 | 0.92 | DYRK1A (0.38) | ABL1BCRHSP90AA1HSP90AB1GSK3B | |
| Formic Acid SCHEMBL5563354 | 0.88 | DYRK1A (0.35) | ABL1BCRHSP90AA1HSP90AB1GSK3B | |
| SCHEMBL1176315 | 0.83 | GSK3B (0.43) | GSK3BRBP4 | |
| SCHEMBL5043738 | 0.83 | GSK3B (0.43) | GSK3BRBP4 | |
| SCHEMBL1176365 | 0.83 | DYRK1A (0.39) | ABL1BCRHSP90AA1HSP90AB1GSK3B | |
| SCHEMBL5043108 | 0.82 | GSK3B (0.42) | GSK3BRBP4 | |
| Hydrochloric Acid SCHEMBL1176734 | 0.82 | GSK3B (0.43) | GSK3BRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396833-B2 | Indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-07-08 | — | — | US | claimed |
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |