Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 17/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048707 | 0.91 | P2RY1 (0.51) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL5046788 | 0.85 | P2RY1 (0.49) | P2RY1 | |
| SCHEMBL5043220 | 0.85 | P2RY1 (0.51) | P2RY1DYRK1ADYRK1B | |
| SCHEMBL5048688 | 0.84 | P2RY1 (0.55) | P2RY1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL5048557 | 0.82 | P2RY1 (0.49) | P2RY1DYRK1ADYRK1B | |
| SCHEMBL5043310 | 0.82 | P2RY1 (0.51) | P2RY1PDE10ADYRK1ADYRK1B | |
| SCHEMBL5028141 | 0.81 | P2RY1 (0.44) | P2RY1DYRK1ADYRK1BKDM4EMEN1 | |
| SCHEMBL1307144 | 0.81 | P2RY1 (0.55) | P2RY1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL5046532 | 0.81 | P2RY1 (0.55) | P2RY1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL5043417 | 0.81 | P2RY1 (0.52) | P2RY1PDE10ADYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706398-B1 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2014-05-21 | — | — | EP | claimed |
| US-7470712-B2 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | claimed |
| US-20050203146-A1 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-09-15 | — | — | US | claimed |
| EP-1706398-B1 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2014-05-21 | — | — | EP | disclosed |
| US-20130078728-A1 | Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203146-A1 | Amino-benzazoles as P2Y1 receptor inhibitors | P2RY1, P2RY11, P2RY2 | P2RY1 1/4885CSNK1A1 1196/4885CSNK1D 1817/4885 |
| US-20130078728-A1 | Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics | SRMS, TMT1A, PTMS | P2RY1 4301/4885CSNK1A1 1311/4885CSNK1D 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.