Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.97 |
| ▸ | RARB | P10826 | 4/20 | 0.90 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.70 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778285 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL371494 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL503568 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10777726 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL3625733 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1163918 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1322922 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7470745 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1469965 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL503352 | 1.00 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 669 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-116136001-B | Carboxylic acid extractant and method for separating impurity aluminum ions from rare earth feed liquid by using same | 厦门稀土材料研究所 | 2024-12-24 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-113903864-A | Organic solar cell and organic-inorganic heterogeneous interface regulation and control method thereof | 浙江大学 | 2022-01-07 | — | — | CN | claimed |
| CN-113194907-A | Particles comprising a colorant and methods of use thereof | 瞬息方案公司 | 2021-07-30 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| WO-2016058991-A1 | POLYMERS FEATURING ENHANCED FLOW | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2016-04-21 | — | — | WO | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| WO-1997027331-A9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | — | 1997-10-09 | — | — | WO | claimed |
| WO-1997027331-A2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE, INC. (US) | 1997-07-31 | — | — | WO | claimed |
| WO-1997027327-A2 | METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL | RAPIGENE, INC. (US) | 1997-07-31 | — | — | WO | claimed |
| US-4179395-A | LIQUID CRYSTALS FOR USE IN DISPLAYS | GENERAL ELECTRIC COMPANY (US) | 1979-12-18 | — | — | US | claimed |
| US-4128496-A | Dichroic liquid crystal compositions | GENERAL ELECTRIC COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-4128497-A | TRISAZO DYE | GENERAL ELECTRIC COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-4122027-A | CONTRAST RATIOS | GENERAL ELECTRIC COMPANY (US) | 1978-10-24 | — | — | US | claimed |
| US-4011173-A | MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-03-08 | — | — | US | claimed |
| US-4002670-A | 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-11 | — | — | US | claimed |
| US-4001137-A | Nematic compounds and mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | TP53 234/4885TSHR 1605/4885PLA2G4B 2095/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | TP53 234/4885TSHR 1605/4885PLA2G4B 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.