Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 19/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8279640 | 0.91 | SLC6A9 (0.66) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL4057663 | 0.81 | SLC6A9 (0.57) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL3885816 | 0.81 | SLC6A9 (0.53) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL18274654 | 0.81 | SLC6A9 (0.59) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL3559578 | 0.80 | SLC6A9 (0.83) | SLC6A9 | |
| SCHEMBL3561972 | 0.79 | KDM4E (0.56) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL760544 | 0.79 | SLC6A9 (0.58) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL761055 | 0.79 | SLC6A9 (0.58) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL3561259 | 0.78 | SLC6A9 (0.56) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL760024 | 0.78 | SLC6A9 (0.56) | SLC6A9KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942733-A2 | RADIOLABELED GLYCINE TRANSPORTER INHIBITORS | Merck & Co., Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007041025-A2 | RADIOLABELED GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2007-04-12 | — | — | WO | disclosed |