Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503769 | 0.79 | KCNH2 (0.33) | NPY1RKCNH2 | |
| SCHEMBL3405719 | 0.77 | NPY1R (0.42) | NPY1RKCNH2 | |
| SCHEMBL962368 | 0.76 | NPY1R (0.43) | NPY1RKCNH2 | |
| SCHEMBL503774 | 0.75 | — | — | |
| SCHEMBL503773 | 0.73 | — | — | |
| SCHEMBL961762 | 0.71 | NPY1R (0.42) | NPY1RKCNH2 | |
| SCHEMBL112996 | 0.70 | HRH4 (0.38) | NPY1RKCNH2 | |
| SCHEMBL113294 | 0.69 | NPY1R (0.44) | NPY1RKCNH2 | |
| SCHEMBL1004698 | 0.69 | NPY1R (0.43) | NPY1RKCNH2 | |
| SCHEMBL965501 | 0.67 | NPY1R (0.47) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028970-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | MSD K.K. (JP) | 2012-02-02 | — | — | US | claimed |
| US-20120028970-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | MSD K.K. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028970-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | AR, NR5A1, ARL1 | NPY1R 354/4885KCNH2 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.