SCHEMBL504029

SCHEMBL504029

COc1ccc(OC)c(CC(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 1.00
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
PTGS1 P23219 1/20 0.56
AKR1C3 P42330 1/20 0.56
AKR1C2 P52895 1/20 0.56
KDM4E B2RXH2 3/20 0.55
IDO1 P14902 2/20 0.54
ADRA1A P35348 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
MTNR1A P48039 1/20 0.54
MTNR1B P49286 1/20 0.54
LCK P06239 1/20 0.52
GAA P10253 1/20 0.51
HTR2A P28223 1/20 0.51
ABL1 P00519 1/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
RECQL P46063 1/20 0.51
RIN1 Q13671 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30512021 1.00 HSD17B10 (1.00) HSD17B10MEN1KMT2APTGS1AKR1C3
Hydrochloric Acid SCHEMBL2527402 0.98 HSD17B10 (0.97) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL28778581 0.91 HSD17B10 (0.82) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL17967503 0.87 HSD17B10 (0.77) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL30831943 0.86 HSD17B10 (0.75) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL5743959 0.86 HSD17B10 (0.75) HSD17B10MEN1KMT2AIDO1ADRA1A
SCHEMBL1097902 0.86 HSD17B10 (0.75) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL7418168 0.85 HSD17B10 (0.74) HSD17B10MEN1KMT2APTGS1AKR1C3
SCHEMBL17764790 0.84 HSD17B10 (0.72) HSD17B10MEN1KMT2AGAA
Hydrochloric Acid SCHEMBL2527027 0.84 HSD17B10 (0.73) HSD17B10MEN1KMT2APTGS1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174800-B Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2023-07-28 CN claimed
CN-112321413-A Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2021-02-05 CN claimed
CN-112321412-A Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2021-02-05 CN claimed
CN-112239402-A Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2021-01-19 CN claimed
CN-112174800-A Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2021-01-05 CN claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
WO-2023170024-A1 CAMK2 MODULATORS AND THEIR USE IN MEDICINE UNIVERSITY OF COPENHAGEN (DK) 2023-09-14 WO disclosed
CN-112174800-B Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2023-07-28 CN disclosed
CN-112174800-B Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2023-07-28 CN disclosed
EP-0116444-A2 Improvements in or relating to benzazepine derivatives ELI LILLY AND COMPANY (US) 1984-08-22 EP disclosed
US-4247597-A Electroscopic carrier particles having a carboxylic acid surface treatment PITNEY BOWES, INC. (US) 1981-01-27 US disclosed
US-4182720-A Process for the preparation of homogentisic lactone IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 HSD17B10 2219/4885MEN1 685/4885KMT2A 1624/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 HSD17B10 2365/4885MEN1 1466/4885KMT2A 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.