Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385703 | 0.94 | TSHR (0.68) | BCHESMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL5037311 | 0.88 | KDM4E (0.70) | BCHETSHRMAPTKDM4ERPS6KB1 | |
| SCHEMBL1386316 | 0.84 | BCHE (0.68) | BCHESMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL5037413 | 0.83 | KDM4E (0.62) | BCHESMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL5041207 | 0.83 | KDM4E (0.65) | SMN1; SMN2TSHRMEN1MAPTKMT2A | |
| SCHEMBL5037898 | 0.83 | KDM4E (0.62) | BCHESMN1; SMN2KDM4ETP53 | |
| SCHEMBL1386849 | 0.82 | TSHR (0.66) | BCHESMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL29728205 | 0.81 | BCHE (0.86) | BCHESMN1; SMN2MAPTTP53 | |
| Methoxymethane SCHEMBL1385816 | 0.81 | TSHR (0.65) | BCHESMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL1385815 | 0.81 | TSHR (0.65) | BCHESMN1; SMN2TSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636215-B1 | FURAZANOBENZIMIDAZOLES | BASILEA PHARMACEUTICA AG (CH) | 2008-01-23 | — | — | EP | claimed |