Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044021 | 0.93 | TP53 (0.63) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL5044698 | 0.93 | TP53 (0.63) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL5047372 | 0.93 | TP53 (0.63) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL5039654 | 0.87 | RARB (0.59) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL5047452 | 0.87 | RARB (0.59) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL11927401 | 0.82 | APP (0.46) | RARBTHRAMEN1USP2ALDH1A1 | |
| SCHEMBL10358713 | 0.81 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7836467 | 0.81 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10785291 | 0.81 | TP53 (0.85) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7733877 | 0.81 | GAA (0.73) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341823-B1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA HOLDING INC (CH) | 2008-10-01 | — | — | EP | disclosed |
| US-7001644-B2 | Surface-active photoinitiators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040034115-A1 | Surface-active photoinitiators | IGM GROUP B.V. (NL) | 2004-02-19 | — | — | US | disclosed |
| EP-1341823-A1 | SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048202-A1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |