⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196665 | 0.81 | — | — | |
| SCHEMBL4970022 | 0.75 | GABRR1 (0.39) | — | |
| SCHEMBL11797163 | 0.73 | — | — | |
| SCHEMBL5395212 | 0.73 | — | — | |
| SCHEMBL16820705 | 0.73 | — | — | |
| SCHEMBL16820919 | 0.73 | — | — | |
| SCHEMBL5748091 | 0.71 | — | — | |
| SCHEMBL10314775 | 0.71 | — | — | |
| SCHEMBL475828 | 0.71 | — | — | |
| SCHEMBL10314780 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145242-A1 | PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. | NIPPON SODA CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| EP-2998298-A1 | PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. | Nippon Soda Co., Ltd. (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8987514-B2 | Compositions and methods for labeling and imaging phospholipids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-24 | — | — | US | disclosed |
| US-8987514-B2 | Compositions and methods for labeling and imaging phospholipids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-24 | — | — | US | disclosed |
| US-8987514-B2 | Compositions and methods for labeling and imaging phospholipids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-24 | — | — | US | disclosed |
| US-20120028290-A1 | Compositions and Methods for Labeling and Imaging Phospholipids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2010091142-A1 | COMPOSITIONS AND METHODS FOR LABELING AND IMAGING PHOSPHOLIPIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-08-12 | — | — | WO | disclosed |