Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5011852 | 0.88 | FPR3 (0.47) | BCHEACHEBACE1TEAD1HRH4 | |
| Trifluoroacetic Acid SCHEMBL5037867 | 0.88 | POLB (0.52) | BCHEACHEBACE1PRCPSMN1; SMN2 | |
| SCHEMBL3355681 | 0.87 | BCHE (0.54) | BCHEACHEBACE1SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL5014957 | 0.86 | SLC6A2 (0.43) | SLC6A2SLC6A4TEAD1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL5040982 | 0.85 | HTR2C (0.58) | BCHEACHEBACE1SMN1; SMN2HRH3 | |
| Trifluoroacetic Acid SCHEMBL5036144 | 0.85 | CARM1 (0.47) | SLC6A2SLC6A3TEAD1 | |
| Trifluoroacetic Acid SCHEMBL5033621 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2 | |
| SCHEMBL28742890 | 0.83 | BCHE (0.50) | BCHEACHEBACE1SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL5040989 | 0.81 | DRD4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2A | |
| Trifluoroacetic Acid SCHEMBL5037785 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622914-A4 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1622914-A2 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | Predix Pharmaceuticals Holdings, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004089312-A2 | NEW PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |