Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5042261 | 0.93 | KCNH2 (0.48) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL5040315 | 0.92 | KCNH2 (0.46) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL2798220 | 0.92 | KCNH2 (0.46) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL5044554 | 0.92 | KCNH2 (0.47) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL2798529 | 0.91 | KCNH2 (0.45) | KCNH2CNR1CNR2MCHR1HTR1A | |
| SCHEMBL5046804 | 0.91 | KCNH2 (0.46) | KCNH2LMNA | |
| SCHEMBL5039995 | 0.90 | KCNH2 (0.48) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL5036618 | 0.90 | KCNH2 (0.47) | KCNH2CNR1CNR2MCHR1LMNA | |
| SCHEMBL12002166 | 0.89 | CNR2 (0.47) | KCNH2CNR1CNR2MCHR1 | |
| SCHEMBL13264609 | 0.88 | CNR2 (0.51) | KCNH2CNR1CNR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524738-B2 | Quinolinones and quinoxalinones as antibacterial composition | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | NQO2, ASNS, NDUFS1 | KCNH2 525/4885CNR1 2005/4885CNR2 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.