Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 8/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 11/20 | 0.45 |
| ▸ | MASP2 | O00187 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041191 | 1.00 | F7 (0.47) | F7ADRA1BF3F2MASP2 | |
| Acetic Acid SCHEMBL5040883 | 0.98 | F7 (0.45) | F7ADRA1BF3F2MASP2 | |
| SCHEMBL5041241 | 0.90 | PKM (0.43) | F7ADRA1BF3F2MASP2 | |
| SCHEMBL5041248 | 0.90 | PKM (0.43) | F7ADRA1BF3F2MASP2 | |
| Hydrochloric Acid SCHEMBL5041028 | 0.86 | F7 (0.43) | F7ADRA1BF3F2MASP2 | |
| Hydrochloric Acid SCHEMBL5041022 | 0.86 | F7 (0.43) | F7ADRA1BF3F2MASP2 | |
| Hydrochloric Acid SCHEMBL5042414 | 0.85 | F7 (0.50) | F7ADRA1BF3F2MASP2 | |
| Acetic Acid SCHEMBL5045452 | 0.85 | F7 (0.54) | F7ADRA1BF3F2MASP2 | |
| SCHEMBL5043466 | 0.84 | PKM (0.45) | PKM | |
| SCHEMBL5043462 | 0.84 | PKM (0.45) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |